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Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype

Tumor-immune cell interactions shape the immune cell phenotype, with microRNAs (miRs) being crucial components of this crosstalk. How they are transferred and how they affect their target landscape, especially in tumor-associated macrophages (TAMs), is largely unknown. Here we report that breast can...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Frank, Ann-Christin, Ebersberger, Stefanie, Fink, Annika F., Lampe, Sebastian, Weigert, Andreas, Schmid, Tobias, Ebersberger, Ingo, Syed, Shahzad Nawaz, Brüne, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408494/
https://ncbi.nlm.nih.gov/pubmed/30850595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08989-2
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