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A Ca(2+)-regulated deAMPylation switch in human and bacterial FIC proteins

FIC proteins regulate molecular processes from bacteria to humans by catalyzing post-translational modifications (PTM), the most frequent being the addition of AMP or AMPylation. In many AMPylating FIC proteins, a structurally conserved glutamate represses AMPylation and, in mammalian FICD, also sup...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Veyron, Simon, Oliva, Giulia, Rolando, Monica, Buchrieser, Carmen, Peyroche, Gérald, Cherfils, Jacqueline
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408439/
https://ncbi.nlm.nih.gov/pubmed/30850593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09023-1
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