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Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers
The liver plays a central role in metabolism; however, xenobiotic metabolism variations between human hepatocytes and those in model organisms create challenges in establishing functional test beds to detect the potential drug toxicity and efficacy of candidate small molecules. In the emerging areas...
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| Pubblicato in: | Cell Metab |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6408324/ https://ncbi.nlm.nih.gov/pubmed/30840913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.02.003 |
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