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Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers
The liver plays a central role in metabolism; however, xenobiotic metabolism variations between human hepatocytes and those in model organisms create challenges in establishing functional test beds to detect the potential drug toxicity and efficacy of candidate small molecules. In the emerging areas...
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| Publicado no: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6408324/ https://ncbi.nlm.nih.gov/pubmed/30840913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.02.003 |
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