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Drug-free Macromolecular Therapeutics Induce Apoptosis in Cells Isolated from Patients with B Cell Malignancies with Enhanced Apoptosis Induction by Pretreatment with Gemcitabine

Drug-free macromolecular therapeutics (DFMT) is a new paradigm for the treatment of B cell malignancies. Apoptosis is initiated by the biorecognition of complementary oligonucleotide motifs at the cell surface resulting in crosslinking of CD20 receptors. DMFT is composed from two nanoconjugates: 1)...

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Foilsithe in:Nanomedicine
Main Authors: Wang, Jiawei, Li, Lian, Yang, Jiyuan, Clair, Phillip M., Glenn, Martha J., Stephens, Deborah M., Radford, D. Christopher, Kosak, Ken M., Deininger, Michael W., Shami, Paul J., Kopeček, Jindřich
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408272/
https://ncbi.nlm.nih.gov/pubmed/30639670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.12.011
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