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Trapping the complex molecular machinery of polyketide and fatty acid synthases with tunable silylcyanohydrin crosslinkers
Many families of natural products are synthesized by large multidomain biological machines commonly referred to as megasynthases. While the advance of mechanism-based tools has opened new windows into the structural features within the protein • protein interfaces guiding carrier protein dependent e...
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| Vydáno v: | Angew Chem Int Ed Engl |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6407627/ https://ncbi.nlm.nih.gov/pubmed/30379389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201806865 |
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