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Synthesis and biological evaluation of ursolic acid derivatives bearing triazole moieties as potential anti-Toxoplasma gondii agents

Ursolic acid (UA), a plant-derived compound, has many properties beneficial to health. In the present study, we synthesised three series of novel UA derivatives and evaluated their anti-Toxoplasma gondii activity both in vitro and in vivo. Most derivatives exhibited an improved anti-T. gondii activi...

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Podrobná bibliografie
Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Luan, Tian, Jin, Chunmei, Jin, Chun-Mei, Gong, Guo-Hua, Quan, Zhe-Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407578/
https://ncbi.nlm.nih.gov/pubmed/30836795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1584622
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