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Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents

New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ), and rotarod neurotoxicity (TOX) tests. Among the compound...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Da-Chuan, Zhang, Hong-Jian, Jin, Chun-Mei, Quan, Zhe-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274423/
https://ncbi.nlm.nih.gov/pubmed/26938519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21030164
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