The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application. The aim of this study was to develop PLGA-based cisplatin-loaded implants and evaluate the antitumor efficacy of c...

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Bibliographic Details
Published in:Drug Deliv
Main Authors: Gao, Li, Cai, Shang, Cai, Awei, Zhao, Yang, Xu, Tangbing, Ma, Yan, Xu, Yan, Wang, Yuan, Wang, Hao, Hu, Yong
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407574/
https://ncbi.nlm.nih.gov/pubmed/30835582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1574938
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