GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish

Although the use of model systems for studying the mechanism of mutations that have a large effect is common, we highlight here the ways that zebrafish-model-system studies of a gene, GRIK5, that contributes to the polygenic liability to develop eye diseases have helped to illuminate a mechanism tha...

詳細記述

保存先:
書誌詳細
出版年:Am J Hum Genet
主要な著者: Unlu, Gokhan, Gamazon, Eric R., Qi, Xinzi, Levic, Daniel S., Bastarache, Lisa, Denny, Joshua C., Roden, Dan M., Mayzus, Ilya, Breyer, Max, Zhong, Xue, Konkashbaev, Anuar I., Rzhetsky, Andrey, Knapik, Ela W., Cox, Nancy J.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407495/
https://ncbi.nlm.nih.gov/pubmed/30827500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.01.017
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料