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GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice

OBJECTIVE: Analogues of GDF15 (Growth Differentiation Factor 15) are promising new anti-obesity therapies as pharmacological treatment with GDF15 results in dramatic reductions of food intake and body weight. GDF15 exerts its central anorexic effects by binding to the GFRAL receptor exclusively expr...

詳細記述

保存先:
書誌詳細
出版年:Mol Metab
主要な著者: Frikke-Schmidt, Henriette, Hultman, Karin, Galaske, Joseph W., Jørgensen, Sebastian B., Myers, Martin G., Seeley, Randy J.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407365/
https://ncbi.nlm.nih.gov/pubmed/30685336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.003
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