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C679X loss-of-function PCSK9 variant is associated with lower fasting glucose in black South African adolescents: Birth to Twenty Plus Cohort
AIM: To evaluate the association between loss-of-function (LOF) PCSK9 variants (A433T/rs28362263 and C679X/rs28362286) and biomarkers of cardiometabolic risk, specifically fasting glucose and low density lipoprotein cholesterol (LDL-C) concentrations. METHODS: Our study comprised 757 male and female...
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| Pubblicato in: | J Clin Transl Endocrinol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6407309/ https://ncbi.nlm.nih.gov/pubmed/30899674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcte.2019.100186 |
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