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Mild Intraocular Pressure Elevation in Mice Reveals Distinct Retinal Ganglion Cell Functional Thresholds and Pressure-Dependent Properties

Elevation of intraocular pressure (IOP) causes retinal ganglion cell (RGC) dysfunction and death and is a major risk factor for glaucoma. We used a bead injection technique to increase IOP in mice of both genders by an average of ∼3 mmHg for 2 weeks. This level of IOP elevation was lower than that a...

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Foilsithe in:J Neurosci
Main Authors: Tao, Xiaofeng, Sabharwal, Jasdeep, Seilheimer, Robert L., Wu, Samuel M., Frankfort, Benjamin J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407300/
https://ncbi.nlm.nih.gov/pubmed/30622167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2085-18.2019
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