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Mild Intraocular Pressure Elevation in Mice Reveals Distinct Retinal Ganglion Cell Functional Thresholds and Pressure-Dependent Properties

Elevation of intraocular pressure (IOP) causes retinal ganglion cell (RGC) dysfunction and death and is a major risk factor for glaucoma. We used a bead injection technique to increase IOP in mice of both genders by an average of ∼3 mmHg for 2 weeks. This level of IOP elevation was lower than that a...

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Опубликовано в: :J Neurosci
Главные авторы: Tao, Xiaofeng, Sabharwal, Jasdeep, Seilheimer, Robert L., Wu, Samuel M., Frankfort, Benjamin J.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407300/
https://ncbi.nlm.nih.gov/pubmed/30622167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2085-18.2019
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