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Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice

Elevated intraocular pressure (IOP) is the major risk factor for glaucoma, a sight threatening disease of retinal ganglion cells (RGCs) and their axons. Despite the central importance of IOP, details of the impact of IOP elevation on RGC gene expression remain elusive. We developed a 4-step immunopa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Yong H., Snook, Joshua D., Ostrin, Edwin J., Kim, Sangbae, Chen, Rui, Frankfort, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385489/
https://ncbi.nlm.nih.gov/pubmed/30796289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39141-1
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