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Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice

Elevated intraocular pressure (IOP) is the major risk factor for glaucoma, a sight threatening disease of retinal ganglion cells (RGCs) and their axons. Despite the central importance of IOP, details of the impact of IOP elevation on RGC gene expression remain elusive. We developed a 4-step immunopa...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Park, Yong H., Snook, Joshua D., Ostrin, Edwin J., Kim, Sangbae, Chen, Rui, Frankfort, Benjamin J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385489/
https://ncbi.nlm.nih.gov/pubmed/30796289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39141-1
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