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Angiotensin II promotes ovarian cancer spheroid formation and metastasis by upregulation of lipid desaturation and suppression of endoplasmic reticulum stress

BACKGROUND: Angiotensin II (ANGII) and its receptor (AGTR1) have been proposed as significant contributors to metastasis in multiple cancers. Further, high AGTR1 levels are associated with poor epithelial ovarian cancer (EOC) outcomes. However, the mechanistic basis for these effects is unknown. Rec...

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Detaylı Bibliyografya
Yayımlandı:J Exp Clin Cancer Res
Asıl Yazarlar: Zhang, Qingyu, Yu, Shan, Lam, Melody Man Ting, Poon, Terence Chuen Wai, Sun, Litao, Jiao, Yufei, Wong, Alice Sze Tsai, Lee, Leo Tsz On
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407256/
https://ncbi.nlm.nih.gov/pubmed/30845964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1127-x
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