Cadherin 11 Inhibition Downregulates β-catenin, Deactivates the Canonical WNT Signalling Pathway and Suppresses the Cancer Stem Cell-Like Phenotype of Triple Negative Breast Cancer

Background: Cancer stem cells (CSCs) promote tumor progression and distant metastasis in breast cancer. Cadherin 11 (CDH11) is overexpressed in invasive breast cancer cells and implicated in distant bone metastases in several cancers. The WNT signalling pathway regulates CSC activity. Growing eviden...

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Bibliografiset tiedot
Julkaisussa:J Clin Med
Päätekijät: Satriyo, Pamungkas Bagus, Bamodu, Oluwaseun Adebayo, Chen, Jia-Hong, Aryandono, Teguh, Haryana, Sofia Mubarika, Yeh, Chi-Tai, Chao, Tsu-Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407101/
https://ncbi.nlm.nih.gov/pubmed/30691241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8020148
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