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Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche

Expansion of hematopoietic stem cells (HSCs) for therapeutic purposes has been a “holy grail” in the field for many years. Ex vivo expansion of HSCs can help to overcome material shortage for transplantation purposes and genetic modification protocols. In this review, we summarize improved understan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Tajer, Parisa, Pike-Overzet, Karin, Arias, Sagrario, Havenga, Menzo, Staal, Frank J.T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407064/
https://ncbi.nlm.nih.gov/pubmed/30781676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020169
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