Targeting Glioblastoma Stem Cells with 2-Deoxy-D-Glucose (2-DG) Potentiates Radiation-Induced Unfolded Protein Response (UPR)

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, and despite optimized treatment options, median survival remains dismal. Contemporary evidence suggests disease recurrence results from expansion of a robustly radioresistant subset of GBM progenitor cells, termed GB...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Shah, Sumedh S., Rodriguez, Gregor A., Musick, Alexis, Walters, Winston M., de Cordoba, Nicolas, Barbarite, Eric, Marlow, Megan M., Marples, Brian, Prince, Jeffrey S., Komotar, Ricardo J., Vanni, Steven, Graham, Regina M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406669/
https://ncbi.nlm.nih.gov/pubmed/30709011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020159
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