Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53

Focal adhesion kinase (FAK) plays an important role in vascular development, including the regulation of endothelial cell (EC) adhesion, migration, proliferation, and survival. 3’-deoxyadenosine (cordycepin) is known to suppress FAK expression, cell migration, and the epithelial–mesenchymal transiti...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Lin, Yi-Ting, Liang, Shu-Man, Wu, Ya-Ju, Wu, Yi-Ju, Lu, Yi-Jhu, Jan, Yee-Jee, Ko, Bor-Sheng, Chuang, Yung-Jen, Shyue, Song-Kun, Kuo, Cheng-Chin, Liou, Jun-Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406613/
https://ncbi.nlm.nih.gov/pubmed/30717276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020168
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