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Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity
Maintaining stemness of leukemic stem cells (LSCs) and reciprocal interactions between leukemia and stromal cells support leukemic progression and resistance to chemotherapy. Targeting the niche-based microenvironment is thus a new approach for leukemia therapy. Cordycepin is an analogue of adenosin...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339716/ https://ncbi.nlm.nih.gov/pubmed/28266575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43930 |
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