Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity

Maintaining stemness of leukemic stem cells (LSCs) and reciprocal interactions between leukemia and stromal cells support leukemic progression and resistance to chemotherapy. Targeting the niche-based microenvironment is thus a new approach for leukemia therapy. Cordycepin is an analogue of adenosin...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Liang, Shu-Man, Lu, Yi-Jhu, Ko, Bor-Sheng, Jan, Yee-Jee, Shyue, Song-Kun, Yet, Shaw-Fang, Liou, Jun-Yang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339716/
https://ncbi.nlm.nih.gov/pubmed/28266575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43930
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