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Increased Risk of Multiple Outpatient Surgeries in African-American Carriers of Transthyretin Val122Ile Mutation Is Modulated by Non-Coding Variants

Background: African-Americans (AAs) have a 3.5% carrier prevalence of Transthyretin (TTR) Val122Ile mutation (rs76992529), which is the genetic cause of a hereditary form of amyloidosis. Methods: We investigated the medical history of Val122Ile carriers and assessed the role of a non-coding variatio...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Polimanti, Renato, Nuñez, Yaira Z., Gelernter, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406512/
https://ncbi.nlm.nih.gov/pubmed/30813263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8020269
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