Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity

We previously demonstrated that cellular aging signals upregulated a secreted class 3 semaphorin E (Sema3E) and its receptor plexinD1 in the adipose tissue of a murine model of dietary obesity and that Sema3E was a chemoattractant, mediating its biological effects by inducing infiltration of plexinD...

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Publicat a:Sci Rep
Autors principals: Yoshida, Yohko, Shimizu, Ippei, Hayashi, Yuka, Ikegami, Ryutaro, Suda, Masayoshi, Katsuumi, Goro, Wakasugi, Takayuki, Nakao, Masaaki, Nakagami, Hironori, Morishita, Ryuichi, Minamino, Tohru
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405888/
https://ncbi.nlm.nih.gov/pubmed/30846754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40325-y
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