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cGMP modulation therapeutics for sickle cell disease

Sickle cell disease (SCD) is an inherited disease caused by the production of abnormal hemoglobin (Hb) S, whose deoxygenation-induced polymerization results in red blood cell (RBC) sickling and numerous pathophysiological consequences. SCD affects approximately 300,000 newborns worldwide each year a...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Conran, Nicola, Torres, Lidiane
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405827/
https://ncbi.nlm.nih.gov/pubmed/30691292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219827276
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