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Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats

Methyl isocyanate (MIC) is a highly toxic industrial chemical causing acute lethality after inhalation. The objective of this study was to determine whether alterations in hemostasis also occur in the immediate hours after exposure. Male rats were exposed to MIC (125-500 ppm) by nose-only vapor inha...

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Detalhes bibliográficos
Publicado no:Drug Chem Toxicol
Main Authors: Rancourt, Raymond C., Rioux, Jacqueline S., Veress, Livia A., Garlick, Rhonda B., Croutch, Claire R., Peters, Eric, Sosna, William, White, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405318/
https://ncbi.nlm.nih.gov/pubmed/30426789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01480545.2018.1517773
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