Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation

Sulfur mustard (SM) inhalation causes airway injury, with enhanced vascular permeability, coagulation, and airway obstruction. The objective of this study was to determine whether recombinant tissue factor pathway inhibitor (TFPI) could inhibit this pathogenic sequence. METHODS: Rats were exposed to...

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Main Authors: Rancourt, Raymond C., Veress, Livia A., Ahmad, Aftab, Hendry-Hofer, Tara B., Rioux, Jacqueline S., Garlick, Rhonda B., White, Carl W.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775856/
https://ncbi.nlm.nih.gov/pubmed/23727623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.05.020
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