Načítá se...

Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA

p53 is a tumor suppressor protein that maintains genome stability, but its Δ133p53β and Δ160p53β isoforms promote breast cancer cell invasion. The sequence truncations in the p53 core domain raise key questions related to their physicochemical properties, including structural stabilities, interactio...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Lei, Jiangtao, Qi, Ruxi, Tang, Yegen, Wang, Wenning, Wei, Guanghong, Nussinov, Ruth, Ma, Buyong
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404584/
https://ncbi.nlm.nih.gov/pubmed/30540922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801973R
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!