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APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice

Development of Alzheimer’s disease (AD) is regulated by interactive effects of genetic and environmental risk factors. The most significant genetic risk factor for AD is the ε4 allele of apolipoprotein E (APOE4), which has been shown to exert greater AD risk in women. An important modifiable AD risk...

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Bibliografske podrobnosti
izdano v:FASEB J
Main Authors: Christensen, Amy, Pike, Christian J.
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404574/
https://ncbi.nlm.nih.gov/pubmed/30509127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801756R
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