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Age-dependent regulation of obesity and Alzheimer-related outcomes by hormone therapy in female 3xTg-AD mice

Depletion of ovarian hormones at menopause is associated with increased Alzheimer’s disease (AD) risk. Hormone loss also increases central adiposity, which promotes AD development. One strategy to improve health outcomes in postmenopausal women is estrogen-based hormone therapy (HT), though its effi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Christensen, Amy, Pike, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456100/
https://ncbi.nlm.nih.gov/pubmed/28575011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178490
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