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Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila

The repeated and improper use of antibiotics had led to an increased number of multiresistant bacteria. Therefore, new lead structures are needed. Here, the synthesis and an expanded structure–activity relationship of the simple and antistaphylococcal amide nematophin from Xenorhabdus nematophila an...

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Pubblicato in:Beilstein J Org Chem
Autori principali: Wesche, Frank, Adihou, Hélène, Wichelhaus, Thomas A, Bode, Helge B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404511/
https://ncbi.nlm.nih.gov/pubmed/30873237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.47
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