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Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila

The repeated and improper use of antibiotics had led to an increased number of multiresistant bacteria. Therefore, new lead structures are needed. Here, the synthesis and an expanded structure–activity relationship of the simple and antistaphylococcal amide nematophin from Xenorhabdus nematophila an...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Wesche, Frank, Adihou, Hélène, Wichelhaus, Thomas A, Bode, Helge B
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404511/
https://ncbi.nlm.nih.gov/pubmed/30873237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.47
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