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A chemoenzymatic synthesis of ceramide trafficking inhibitor HPA-12
A chemoenzymatic synthesis of the title compound has been developed using an efficient and highly enantioselective lipase-catalyzed acylation in a hydrophobic ionic liquid, [bmim][PF(6)], followed by a diastereoselective asymmetric dihydroxylation as the key steps for incorporating the stereogenic c...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404422/ https://ncbi.nlm.nih.gov/pubmed/30873232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.42 |
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