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Thiol-free chemoenzymatic synthesis of β-ketosulfides

A preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipase-catalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor. This methodology for the selective synthesis of a set...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Heredia, Adrián A, López-Vidal, Martín G, Kurina-Sanz, Marcela, Bisogno, Fabricio R, Peñéñory, Alicia B
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404416/
https://ncbi.nlm.nih.gov/pubmed/30873224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.34
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