Establishment and Maintenance of Chromatin Architecture Are Promoted Independently of Transcription by the Histone Chaperone FACT and H3-K56 Acetylation in Saccharomyces cerevisiae

FACT (FAcilitates Chromatin Transcription/Transactions) is a histone chaperone that can destabilize or assemble nucleosomes. Acetylation of histone H3-K56 weakens a histone–DNA contact that is central to FACT activity, suggesting that this modification could affect FACT functions. We tested this by...

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Veröffentlicht in:Genetics
Hauptverfasser: McCullough, Laura L., Pham, Trang H., Parnell, Timothy J., Connell, Zaily, Chandrasekharan, Mahesh B., Stillman, David J., Formosa, Tim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2019
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Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404263/
https://ncbi.nlm.nih.gov/pubmed/30679261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301853
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