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Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer

The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) is upregulated in head and neck squamous cell carcinomas (HNSCCs) and expressed as at least seven isoforms in humans. Only two of these isoforms are capable of binding to RNA containing G-quadruplex structures. We suggest that t...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: McClure, Jesse J., Palanisamy, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404231/
https://ncbi.nlm.nih.gov/pubmed/30755307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2018.12.001
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