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rAAVrh74.MCK.GALGT2 Protects against Loss of Hemodynamic Function in the Aging mdx Mouse Heart

Dilated cardiomyopathy is a common cause of death in patients with Duchenne muscular dystrophy (DMD). Gene therapies for DMD must, therefore, have a therapeutic impact in cardiac as well as skeletal muscles. Our previous studies have shown that GALGT2 overexpression in mdx skeletal muscles can preve...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Xu, Rui, Jia, Ying, Zygmunt, Deborah A., Martin, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403484/
https://ncbi.nlm.nih.gov/pubmed/30711447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.01.005
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