Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells

Cell-processed therapeutic products (CTPs) derived from human pluripotent stem cells (hPSCs) have innovative applications in regenerative medicine. However, undifferentiated hPSCs possess tumorigenic potential; thus, sensitive methods for the detection of residual undifferentiated hPSCs are essentia...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kono, Ken, Sawada, Rumi, Kuroda, Takuya, Yasuda, Satoshi, Matsuyama, Satoko, Matsuyama, Akifumi, Mizuguchi, Hiroyuki, Sato, Yoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403330/
https://ncbi.nlm.nih.gov/pubmed/30842516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36848-5
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