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Bacillus Calmette-Guérin Induces PD-L1 Expression on Antigen-Presenting Cells via Autocrine and Paracrine Interleukin-STAT3 Circuits

Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB), and is also used as an immunotherapy for bladder cancer and other malignancies due to its immunostimulatory properties. Mycobacteria spp., however, are well known for their numerous immune evasion mechanisms that limi...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Copland, Alastair, Sparrow, Adam, Hart, Peter, Diogo, Gil Reynolds, Paul, Mathew, Azuma, Miyuki, Reljic, Rajko
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403281/
https://ncbi.nlm.nih.gov/pubmed/30842561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40145-0
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