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Bacillus Calmette-Guérin Induces PD-L1 Expression on Antigen-Presenting Cells via Autocrine and Paracrine Interleukin-STAT3 Circuits

Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB), and is also used as an immunotherapy for bladder cancer and other malignancies due to its immunostimulatory properties. Mycobacteria spp., however, are well known for their numerous immune evasion mechanisms that limi...

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Foilsithe in:Sci Rep
Main Authors: Copland, Alastair, Sparrow, Adam, Hart, Peter, Diogo, Gil Reynolds, Paul, Mathew, Azuma, Miyuki, Reljic, Rajko
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403281/
https://ncbi.nlm.nih.gov/pubmed/30842561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40145-0
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