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How ARVC-Related Mutations Destabilize Desmoplakin: An MD Study

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a familial heart disease linked to mutations in several desmosomal proteins, but the specific effects of these mutations on the molecular level are poorly understood. Among the many documented ARVC-related genetic variants, a striking hotspot...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Daday, Csaba, Mateyka, Laura Marlene, Gräter, Frauke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403075/
https://ncbi.nlm.nih.gov/pubmed/30773294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.023
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