Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells

Aim: Acyl-CoA cholesterol acyltransferase 1 (ACAT1) esterifies free cholesterol to cholesteryl esters (CE), which are subsequently hydrolyzed by neutral cholesterol ester hydrolase 1 (NCEH1). The elimination of ACAT1 in vitro reduces the amounts of CE accumulated in Nceh1-deficient macrophages. The...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Yamazaki, Hisataka, Takahashi, Manabu, Wakabayashi, Tetsuji, Sakai, Kent, Yamamuro, Daisuke, Takei, Akihito, Takei, Shoko, Nagashima, Shuichi, Yagyu, Hiroaki, Sekiya, Motohiro, Ebihara, Ken, Ishibashi, Shun
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Atherosclerosis Society 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402884/
https://ncbi.nlm.nih.gov/pubmed/30282838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.44040
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados