The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation

Human endogenous retroviruses (HERVs) play pivotal roles in the development of breast cancer. However, the detailed mechanisms of noncoding HERVs remain elusive. Here, our genome-wide transcriptome analysis of HERVs revealed that a primate long noncoding RNA, which we dubbed TROJAN, was highly expre...

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Vydáno v:Sci Adv
Hlavní autoři: Jin, Xi, Xu, Xiao-En, Jiang, Yi-Zhou, Liu, Yi-Rong, Sun, Wei, Guo, Ya-Jie, Ren, Yi-Xing, Zuo, Wen-Jia, Hu, Xin, Huang, Sheng-Lin, Shen, Hong-Jie, Lan, Fei, He, Yun-Fei, Hu, Guo-Hong, Di, Gen-Hong, He, Xiang-Huo, Li, Da-Qiang, Liu, Suling, Yu, Ke-Da, Shao, Zhi-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402854/
https://ncbi.nlm.nih.gov/pubmed/30854423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat9820
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