The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation

Human endogenous retroviruses (HERVs) play pivotal roles in the development of breast cancer. However, the detailed mechanisms of noncoding HERVs remain elusive. Here, our genome-wide transcriptome analysis of HERVs revealed that a primate long noncoding RNA, which we dubbed TROJAN, was highly expre...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Jin, Xi, Xu, Xiao-En, Jiang, Yi-Zhou, Liu, Yi-Rong, Sun, Wei, Guo, Ya-Jie, Ren, Yi-Xing, Zuo, Wen-Jia, Hu, Xin, Huang, Sheng-Lin, Shen, Hong-Jie, Lan, Fei, He, Yun-Fei, Hu, Guo-Hong, Di, Gen-Hong, He, Xiang-Huo, Li, Da-Qiang, Liu, Suling, Yu, Ke-Da, Shao, Zhi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402854/
https://ncbi.nlm.nih.gov/pubmed/30854423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat9820
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