CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells

Mutations in the dystrophin gene cause Duchenne muscular dystrophy (DMD), which is characterized by lethal degeneration of cardiac and skeletal muscles. Mutations that delete exon 44 of the dystrophin gene represent one of the most common causes of DMD and can be corrected in ~12% of patients by edi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Min, Yi-Li, Li, Hui, Rodriguez-Caycedo, Cristina, Mireault, Alex A., Huang, Jian, Shelton, John M., McAnally, John R., Amoasii, Leonela, Mammen, Pradeep P. A., Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402849/
https://ncbi.nlm.nih.gov/pubmed/30854433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav4324
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars