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Rett syndrome: insights into genetic, molecular and circuit mechanisms

Rett syndrome (RTT) is a severe neurological disorder caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2). Almost two decades of research into RTT have greatly advanced our understanding of the function and regulation of the multifunctional protein MeCP2. Here, we review re...

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Bibliografiske detaljer
Udgivet i:Nat Rev Neurosci
Main Authors: Ip, Jacque P. K., Mellios, Nikolaos, Sur, Mriganka
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402579/
https://ncbi.nlm.nih.gov/pubmed/29740174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41583-018-0006-3
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