Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome

Rett Syndrome is a neurodevelopmental disorder that arises from mutations in the X-linked gene methyl-CpG binding protein 2 (MeCP2). MeCP2 has a large number of targets and a wide range of functions, suggesting the hypothesis that functional signaling mechanisms upstream of synaptic and circuit matu...

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Main Authors: Castro, Jorge, Garcia, Rodrigo I., Kwok, Showming, Banerjee, Abhishek, Petravicz, Jeremy, Woodson, Jonathan, Mellios, Nikolaos, Tropea, Daniela, Sur, Mriganka
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103342/
https://ncbi.nlm.nih.gov/pubmed/24958891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311685111
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