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Anti-inflammatory action of β-hydroxybutyrate via modulation of PGC-1α and FoxO1, mimicking calorie restriction

β-Hydroxybutyrate (HB) is a ketone body used as an energy source that has shown anti-inflammatory effects similar to calorie restriction (CR); Here, PGC-1α, an abundantly expressed co-factor in the kidney, was reported to interact with both FoxO1 and NF-κB although the definitive interactive mechani...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Kim, Dae Hyun, Park, Min Hi, Ha, Sugyeong, Bang, Eun Jin, Lee, Yujeong, Lee, A Kyoung, Lee, Jaewon, Yu, Byung Pal, Chung, Hae Young
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402511/
https://ncbi.nlm.nih.gov/pubmed/30811347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101838
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