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Aged kidneys are refractory to autophagy activation in a rat model of renal ischemia-reperfusion injury

BACKGROUND: Ischemia-reperfusion (I/R) injury is the most common cause of acute kidney injury (AKI). Numerous therapeutic approaches for I/R injury have been studied, including autophagy, particularly in animal models of renal I/R injury derived from young or adult animals. However, the precise role...

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Опубликовано в: :Clin Interv Aging
Главные авторы: Diao, Changhui, Wang, Lei, Liu, Hao, Du, Yang, Liu, Xiuheng
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402441/
https://ncbi.nlm.nih.gov/pubmed/30880933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S197444
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