Cellular Plasticity of Defa4(Cre)-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury

BACKGROUND & AIMS: Loss of leucine-rich repeat-containing G-protein–coupled receptor 5–positive crypt base columnar cells provides permissive conditions for different facultative stem cell populations to dedifferentiate and repopulate the stem cell compartment. In this study, we used a defensin...

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Veröffentlicht in:Cell Mol Gastroenterol Hepatol
Hauptverfasser: Jones, Jennifer C., Brindley, Constance D., Elder, Nicholas H., Myers, Martin G., Rajala, Michael W., Dekaney, Christopher M., McNamee, Eoin N., Frey, Mark R., Shroyer, Noah F., Dempsey, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402430/
https://ncbi.nlm.nih.gov/pubmed/30827941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.11.004
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