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TRIM69 inhibits cataractogenesis by negatively regulating p53

Ultraviolet B (UVB) irradiation can induce reactive oxygen species (ROS) production and apoptosis in human lens epithelial cells (HLECs), thus leading to the formation of cataracts. We studied the role of tripartite motif 69 (TRIM69) in cataract formation. The expression of TRIM69 protein was down-r...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Rong, Xianfang, Rao, Jun, Li, Dan, Jing, Qinghe, Lu, Yi, Ji, Yinghong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402377/
https://ncbi.nlm.nih.gov/pubmed/30844644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101157
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