TRIM69 inhibits cataractogenesis by negatively regulating p53

Ultraviolet B (UVB) irradiation can induce reactive oxygen species (ROS) production and apoptosis in human lens epithelial cells (HLECs), thus leading to the formation of cataracts. We studied the role of tripartite motif 69 (TRIM69) in cataract formation. The expression of TRIM69 protein was down-r...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Rong, Xianfang, Rao, Jun, Li, Dan, Jing, Qinghe, Lu, Yi, Ji, Yinghong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402377/
https://ncbi.nlm.nih.gov/pubmed/30844644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101157
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