Structural Basis of Nanobodies Targeting the Prototype Norovirus

Human norovirus infections are a major disease burden. In this study, we analyzed three new norovirus-specific Nanobodies that interacted with the prototype human norovirus (i.e., genogroup I genotype 1 [GI.1]). We showed that the Nanobodies bound on the side (Nano-7 and Nano-62) and top (Nano-94) o...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Ruoff, Kerstin, Kilic, Turgay, Devant, Jessica, Koromyslova, Anna, Ringel, Alessa, Hempelmann, Alexander, Geiss, Celina, Graf, Juliane, Haas, Michelle, Roggenbach, Imme, Hansman, Grant
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Structure and Assembly
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401464/
https://ncbi.nlm.nih.gov/pubmed/30602609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02005-18
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